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GLP-1 Weight Loss · 50 States

Lose 15–20% of your body weight.

Personalized GLP-1 therapy compounded for your medical needs by licensed U.S. pharmacies. Semaglutide and tirzepatide injections, oral alternatives, and microdosing programs — delivered to your door.

BMI ≥27 eligible
Ages 18–74
Labs included
FSA / HSA accepted
Your starting weight
220lbs
120 lbs 400 lbs
You could lose
33–44lbs
In approximately 1 year based on clinical studies of semaglutide and tirzepatide at the highest doses, paired with diet and exercise.
Start my assessment

Safety info: GLP-1 medications may have serious side effects, including possible thyroid tumors. Do not use if you or your family have a history of MTC or MEN 2. Full safety info.

Treatment Options

A medication designed for you.

Your clinician selects from semaglutide injections, tirzepatide injections, sublingual oral formulations, and gentler microdosing programs — based on your goals, history, and side-effect profile.

In stock

Semaglutide Injection

Personalized care — 5 dosing levels

  • Average 14.9% body weight loss in 1 year
  • Weekly self-administered injection
  • 6 personalized formulation options
From $179/mo
See pricing
Best results
In stock

Tirzepatide Injection

Personalized care — dual GLP-1/GIP

  • Average 20.9% body weight loss in 1 year
  • Dual receptor — GLP-1 + GIP
  • 6 personalized formulation options
From $269/mo
See pricing
New In stock

Semaglutide Oral

Personalized care — sublingual ODT

  • No needles — daily sublingual tablet
  • Ideal for needle-averse patients
  • 3 dosing levels
From $209/mo
See pricing
Microdosing Program

A gentler way forward.

Microdosing programs combine low-dose GLP-1 with co-formulated NAD+, L-Carnitine, B12, and other targeted nutrients. Broader eligibility (BMI 20+), fewer side effects, and built for sustainable change — not dramatic loss.

See microdosing pricing
From
$149/mo
52-week program · BMI 20+ eligible
10 Personalized Options

The right formula for your body.

Your Ascenva clinician selects from ten distinct compounded GLP-1 formulations, each engineered for a specific medical indication. Tell us what you're working with — we'll match you to the right one.

01
Muscle Wastage Protection
GLP-1 paired with B12, methionine, and choline to preserve lean muscle mass.
02
Side-Effect Mitigation
Gentle titration with inositol and B12 for nausea-prone or sensitive patients.
03
Mental Acuity & Longevity
Co-formulated with NAD+ and L-Carnitine for cognitive and cellular support.
04
Needle Aversion / Muscle Care
Oral sublingual GLP-1 with muscle-preserving co-formulation.
05
Needle-Free Maintenance
Lower-dose oral GLP-1/GIP for sustained weight maintenance after initial loss.
06
Cognitive & Longevity Oral
Oral formulation with NAD+ and L-Carnitine for energy and brain support.
07
A1C & Hormonal Regulation
For prediabetes, PCOS, menstrual irregularity. Co-formulated with inositol.
08
Alcohol Reduction Support
For patients seeking to reduce alcohol consumption alongside weight loss.
09
Smoking Cessation Support
For patients combining nicotine reduction with metabolic improvement.
10
Sleep & Recovery
With magnesium, L-Theanine and B12 for sleep regulation and recovery.

Eligibility and final formulation are determined by your clinician based on your medical history, labs, and goals. Not all patients will qualify for every option.

Membership & Pricing

Lock in your lowest rate.

The longer your commitment, the lower your monthly price. All plans include unlimited clinician messaging, labs, and dose adjustments. Cancel anytime.

Semaglutide Injection

Most popular

Personalized GLP-1 compounded by U.S. pharmacy

$ 179 /month
Billed as $2,327 annually · Ships every 4 weeks
  • Average 14.9% body weight loss
  • Unlimited provider messaging
  • Labs included & shipped supplies
  • 6 personalized formulation options
Start with Semaglutide

Semaglutide Oral

No needles

Sublingual ODT — daily tablet

$ 209 /month
Billed as $2,717 annually · Ships every 4 weeks
  • No injection — sublingual daily
  • Unlimited provider messaging
  • Labs included
  • 3 dosing levels
Start with Oral

Microdosing Program

BMI 20+

GLP-1 + targeted nutrients

$ 149 /month
Billed as $1,937 annually · Ships every 4 weeks
  • 7 program options (Energy, Sleep, A1C, etc.)
  • Broader eligibility — BMI >20
  • Co-formulated NAD+, B12, L-Carnitine
  • Oral or injection options
Start microdosing

All plans include unlimited messaging, dose adjustments, and labs. Final medication and dosing is determined by your clinician based on your assessment.

5 Simple Steps

From assessment to first dose in a week.

1

Take the assessment

Answer questions about your health, weight history, and goals. About 60 seconds.

2

Clinician review

A licensed U.S. provider reviews your case and selects your personalized formulation within 24 hours.

3

Medication ships

If approved, your compounded medication ships from a U.S. pharmacy and arrives in 1–4 days.

4

Start losing weight

Follow your titration schedule with unlimited messaging support from your care team.

Start my assessment
Weight Loss FAQ

Questions, answered.

For our GLP-1 weight loss program, eligibility is generally BMI ≥27, or BMI ≥25 with a weight-related comorbidity. Ages 18–74 to start treatment (patients may continue past 74 based on clinical evaluation). Our Microdosing program has broader eligibility at BMI ≥20.

All final eligibility decisions are made by your licensed clinician based on your full medical history.

Semaglutide is a single-receptor GLP-1 agonist with average weight loss of ~14.9% over 1 year in clinical studies. Tirzepatide is a dual-receptor GLP-1/GIP agonist showing higher average loss of ~20.9% in studies. Tirzepatide tends to deliver stronger results but is priced higher. Your clinician will recommend based on your goals, history, and tolerance.

Wegovy and Ozempic contain semaglutide. Zepbound and Mounjaro contain tirzepatide. Ascenva's personalized formulations use the same active ingredients (semaglutide and tirzepatide), but our compounded versions are personalized by U.S. licensed pharmacies to your medical needs. They are not the same product as the branded medications, and compounded medications are not FDA-approved.

Common side effects include nausea, vomiting, upset stomach, constipation, and diarrhea — particularly during initial dosing and titration. Most resolve as your body adjusts. Your clinician can prescribe ondansetron for nausea if needed.

Serious but rare side effects include thyroid tumors, pancreatitis, and gallbladder issues. Do not use if you or your family have a history of medullary thyroid cancer (MTC) or Multiple Endocrine Neoplasia syndrome type 2 (MEN 2). See full safety information below.

Pricing starts at $149/month for our 52-week Microdosing program and $179/month for Semaglutide on the same plan. Shorter commitments are available at $179–$339 for the 4-week tier. All medication, clinician access, and labs are included.

Yes, we accept FSA and HSA cards. We also accept Visa, Mastercard, Apple Pay, and Google Pay. We do not currently accept American Express or directly bill insurance.

Yes. You can cancel or pause your membership from your member portal at any time, no questions asked. Refunds are available for any month where medication has not yet been ordered for shipment.

Important Safety Information — GLP-1 Medications

Do not use semaglutide or tirzepatide if you or any of your family have ever had a type of thyroid cancer called medullary thyroid carcinoma (MTC), or if you have Multiple Endocrine Neoplasia syndrome type 2 (MEN 2).

GLP-1 medications may cause serious side effects, including inflammation of the pancreas (pancreatitis), gallbladder problems, low blood sugar, kidney problems, serious allergic reactions, changes in vision, increased heart rate, and depression or thoughts of suicide.

Common side effects include nausea, diarrhea, vomiting, constipation, stomach pain, headache, tiredness, upset stomach, dizziness, bloating, belching, gas, and stomach flu.

Tell your healthcare provider if you are pregnant, plan to become pregnant, or are breastfeeding. Semaglutide and tirzepatide should not be used during pregnancy.

This is not a complete list of side effects. For more information, talk to your Ascenva clinician or read the full safety information here.

Compounded medication disclosure: Ascenva Labs personalized care medications are compounded by U.S. state-licensed 503A and 503B pharmacies. Compounded medications are not FDA-approved. The active pharmaceutical ingredients (semaglutide, tirzepatide) used in our formulations are FDA-regulated. All compounding pharmacies we work with follow USP standards and applicable state regulations.

Ready to start feeling like yourself again?

Take the 60-second assessment. Get matched to a clinician. Start treatment within the week.

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