GLP-1 Weight Loss · 50 states

GLP-1 weight loss, personalized to you.

Semaglutide, tirzepatide, oral and microdosing programs — compounded for your medical needs by licensed U.S. pharmacies, reviewed by a real clinician.

Check eligibility — free See pricing

Most adults BMI ≥27 qualify Ages 18–74 Labs included HSA / FSA eligible

GLP-1 medications may have serious side effects, including possible thyroid tumors. Do not use if you or your family have a history of MTC or MEN 2. Full safety info.

A woman checking her personalized Ascenva plan

Compounded for youMatched to your goals & toleranceRx · U.S. pharmacy

Treatment options

A medication designed for you.

Your clinician selects from injections, oral, and gentler microdosing — based on your goals, history, and side-effect profile.

New to GLP-1? Many members start with oral semaglutide. Want our most advanced option? Tirzepatide is our dual-action GLP-1/GIP formula.

Semaglutide Injection

In stockWeekly

Weekly self-administered injection
Single GLP-1 receptor mechanism
6 personalized formulation options

From$179/mo

Start with Semaglutide

Tirzepatide Injection

In stockMost advancedDual-action

Weekly self-administered injection
Dual GLP-1 + GIP receptor mechanism
6 personalized formulation options

From$269/mo

Start with Tirzepatide

Semaglutide Oral

Popular to startNo needles

No needles — daily sublingual tablet
Ideal for needle-averse patients
3 dosing levels

From$209/mo

Start with Oral

Microdosing Program

BMI 20+Gentler

Low-dose GLP-1 + NAD+, B12, L-Carnitine
Broader eligibility — BMI 20+
Built for sustainable change

From$149/mo

Start microdosing

Not sure which is right for you? Take the 60-second quiz and your clinician will match you. Match me

Microdosing

A gentler way forward.

Low-dose GLP-1 co-formulated with NAD+, L-Carnitine, B12 and targeted nutrients. Broader eligibility, fewer side effects, and built for sustainable change — not dramatic loss.

Muscle & EnergyMental AcuitySleep SupportA1C Support

From $149 /month · 52-week program · BMI 20+ eligible See microdosing

Ten personalized options

The right formula for your body.

Your clinician selects from ten distinct compounded GLP-1 formulations, each engineered for a specific medical indication. Tell us what you're working with — we'll match you.

Muscle, metabolism & tolerance

Muscle Wastage Protection

GLP-1 with B12, methionine and choline to preserve lean muscle mass.

Side-Effect Mitigation

Gentle titration with inositol and B12 for nausea-prone or sensitive patients.

A1C & Hormonal Regulation

For prediabetes, PCOS and menstrual irregularity. Co-formulated with inositol.

Cognitive & longevity

Mental Acuity & Longevity

Co-formulated with NAD+ and L-Carnitine for cognitive and cellular support.

Cognitive & Longevity Oral

Oral formulation with NAD+ and L-Carnitine for energy and brain support.

Sleep & Recovery

With magnesium, L-Theanine and B12 for sleep regulation and recovery.

Needle-free & lifestyle support

Needle Aversion / Muscle Care

Oral sublingual GLP-1 with muscle-preserving co-formulation.

Needle-Free Maintenance

Lower-dose oral GLP-1/GIP for sustained maintenance after initial loss.

Alcohol Reduction Support

For patients seeking to reduce alcohol consumption alongside weight loss.

Smoking Cessation Support

For patients combining nicotine reduction with metabolic improvement.

Eligibility and final formulation are determined by your clinician based on your medical history, labs, and goals. Not all patients will qualify for every option.

Membership & pricing

Lock in your lowest rate.

The longer your plan, the more you save — up to 20% off. Every plan includes clinician messaging, labs, and dose adjustments. Cancel anytime.

4-Week 12-Week Save 12% 24-Week Save 20% 52-Week Best value

Labs, messaging & supplies included in every plan

Semaglutide

Personalized GLP-1, compounded by a U.S. pharmacy.

$179/mo

Best-value plan · ships every 4 weeks

Single GLP-1 receptor mechanism
Unlimited provider messaging
Labs included & supplies shipped

Start with Semaglutide

Most advanced

Tirzepatide

Dual GLP-1/GIP — prescribed by your clinician.

$269/mo

Best-value plan · ships every 4 weeks

Dual-receptor GLP-1/GIP mechanism
Unlimited provider messaging
Labs included & supplies shipped

Start with Tirzepatide

Popular to start

Semaglutide Oral

Sublingual daily tablet — no needles.

$209/mo

Best-value plan · ships every 4 weeks

No injection — sublingual daily
Unlimited provider messaging
Labs included

Start with Oral

Microdosing

GLP-1 + targeted nutrients. Broader eligibility.

$149/mo

Best-value plan · ships every 4 weeks

7 program options (Energy, Sleep, A1C…)
Broader eligibility — BMI 20+
Co-formulated NAD+, B12, L-Carnitine

Start microdosing

All plans include unlimited messaging, dose adjustments, and labs. Final medication and dosing are determined by your clinician based on your assessment. Shorter commitments available from the 4-week tier.

4 simple steps

From assessment to first dose in a week.

Take the assessment

Answer questions about your health, weight history, and goals. About 60 seconds.

Clinician review

A licensed U.S. provider reviews your case and selects your formulation within 24 hours.

Medication ships

If approved, your compounded medication ships from a U.S. pharmacy and arrives in 1–4 days. If you're not approved, you won't be charged.

Ongoing support

Follow your titration schedule with unlimited messaging, dose adjustments, and labs — all included.

Start my assessment

"What impressed me most was the level of support. I had questions throughout the process, and I always felt like I knew what the next step was."

Jennifer M.San Diego, CA · Verified member

"For the first time, I feel like I'm working toward something sustainable. Having professional guidance and a clear plan has made the experience completely different."

James B.Denver, CO · Verified member

Ready to feel like yourself again?

Take the 60-second assessment, get matched to a clinician, and start treatment within the week.

Check my eligibility — free No credit card required. Cancel anytime. Individual results vary.

Weight loss FAQ

Questions, answered.

How much does it cost — and can I use FSA/HSA?+

Pricing starts at $149/month for our 52-week Microdosing program and $179/month for Semaglutide on the same plan. Shorter commitments are available at $179–$339 for the 4-week tier. All medication, clinician access, and labs are included. Yes — we accept FSA and HSA cards, plus Visa, Mastercard, Apple Pay, and Google Pay. We do not currently accept American Express or directly bill insurance.

Who is eligible for Ascenva GLP-1 weight loss?+

For our GLP-1 program, eligibility is generally BMI ≥27, or BMI ≥25 with a weight-related comorbidity. Ages 18–74 to start treatment (patients may continue past 74 based on clinical evaluation). Our Microdosing program has broader eligibility at BMI ≥20. All final eligibility decisions are made by your licensed clinician based on your full medical history.

What's the difference between Semaglutide and Tirzepatide?+

Semaglutide is a single-receptor GLP-1 agonist. Tirzepatide is a dual-receptor GLP-1/GIP agonist. Your licensed clinician will recommend the option that is appropriate for you based on your goals, history, and tolerance. Compounded formulations are not FDA-approved, and individual results vary.

How do Ascenva formulations compare to brand-name medications?+

Ascenva's personalized formulations are compounded medications prepared by U.S. state-licensed 503A and 503B pharmacies. They are not the same as, are not generic versions of, and have not been demonstrated to have the same safety or efficacy as, any brand-name medication. Compounded medications are not FDA-approved. Your Ascenva clinician determines the appropriate personalized formulation based on your individual medical needs.

What side effects should I expect?+

Common side effects include nausea, vomiting, upset stomach, constipation, and diarrhea — particularly during initial dosing and titration. Most resolve as your body adjusts. Your clinician can prescribe ondansetron for nausea if needed. Serious but rare side effects include thyroid tumors, pancreatitis, and gallbladder issues. Do not use if you or your family have a history of medullary thyroid cancer (MTC) or Multiple Endocrine Neoplasia syndrome type 2 (MEN 2). See full safety information below.

Can I cancel anytime?+

Yes. You can cancel or pause your membership from your member portal at any time, no questions asked. Refunds are available for any month where medication has not yet been ordered for shipment.

Important Safety Information — GLP-1 Medications

Do not use semaglutide or tirzepatide if you or any of your family have ever had a type of thyroid cancer called medullary thyroid carcinoma (MTC), or if you have Multiple Endocrine Neoplasia syndrome type 2 (MEN 2).

GLP-1 medications may cause serious side effects, including inflammation of the pancreas (pancreatitis), gallbladder problems, low blood sugar, kidney problems, serious allergic reactions, changes in vision, increased heart rate, and depression or thoughts of suicide.

Common side effects include nausea, diarrhea, vomiting, constipation, stomach pain, headache, tiredness, upset stomach, dizziness, bloating, belching, gas, and stomach flu.

Tell your healthcare provider if you are pregnant, plan to become pregnant, or are breastfeeding. Semaglutide and tirzepatide should not be used during pregnancy. This is not a complete list of side effects. For more information, talk to your Ascenva clinician or read the full safety information here.

Compounded medication disclosure: Ascenva Labs personalized care medications are compounded by U.S. state-licensed 503A and 503B pharmacies. Compounded medications are not FDA-approved. They are not the same as, nor generic versions of, any FDA-approved drug, and their safety and efficacy have not been evaluated or approved by the FDA. All compounding pharmacies we work with follow USP standards and applicable state regulations.